Clinical Neurosurgery

Spine Surgery

Spine Surgery

What You'll Learn

  • ACDF is the workhorse for 1–2 level cervical disc herniation causing radiculopathy or myelopathy; posterior approaches (laminectomy/laminoplasty) are preferred for ≥3 levels
  • Cauda equina syndrome is a surgical emergency — bilateral leg pain/weakness, saddle anesthesia, urinary retention; decompression ideally within 24 hours
  • Cervical myelopathy: surgery indicated for moderate-severe disease (mJOA <15) or progressive deficits; approach dictated by number of levels and alignment
  • Fusion indications: instability, spondylolisthesis, deformity correction, post-tumor resection; avoid unnecessary fusion (risk of adjacent segment disease)
  • Metastatic cord compression: NOMS framework guides management; Patchell trial showed surgery + RT superior to RT alone for single-level compression
  • SPORT trial: surgery for lumbar disc herniation provides faster improvement but long-term outcomes converge with conservative treatment
HighYield Pearls
  • Cauda equina syndrome: bilateral LE weakness + saddle anesthesia + urinary retention/incontinence + bowel dysfunction → EMERGENT MRI + decompression within 24–48h; central disc herniation at L4–L5 / L5–S1 most common culprit
  • Metastatic epidural cord compression: give dexamethasone 16 mg/day promptly (oral or equivalent IV) for suspected MSCC with neurologic symptoms/signs (NICE NG234); avoid steroids before tissue diagnosis when lymphoma is suspected unless urgent neurologic compromise requires treatment; urgent MRI whole spine + neurosurgery and rad-onc consult for decompression and/or radiation (Patchell — surgery + RT > RT alone)
  • Spinal epidural abscess: back pain + fever + neuro deficit in IV drug use / diabetes / recent procedure → urgent contrast MRI and antibiotics required; surgical drainage plus antibiotics is standard when there is neurologic deficit, progression, spinal instability, sepsis, or failure of medical therapy; carefully selected neurologically intact patients with an identified organism and close monitoring may be treated medically
  • Cervical myelopathy: progressive gait/balance loss + hand clumsiness + Hoffmann/Babinski + hyperreflexia + Lhermitte; T2 cord hyperintensity at compression level → surgical decompression (ACDF for 1–2 levels, laminoplasty/laminectomy + fusion for ≥3 levels)
  • Anterior spinal cord infarction: abdominal aortic dissection / cross-clamp / atherosclerosis → paraplegia + bilateral pain/temperature loss + sphincter dysfunction with PRESERVED proprioception/vibration (dorsal columns spared)
  • Lumbar stenosis: neurogenic claudication worse with standing/walking, better with FLEXION/sitting (shopping-cart sign); MRI confirms; conservative first, laminectomy ± fusion if recalcitrant
  • Chiari I: cerebellar tonsils >5 mm below foramen magnum + tussive (Valsalva-induced) occipital headache + neck pain + ataxia ± syrinx → suboccipital decompression (duraplasty vs not is controversial)
  • Syringomyelia: central cord cavity → suspended bilateral UE dissociated sensory loss (pain/temp lost, vibration/proprioception spared) + LMN weakness ± Charcot joints; address underlying Chiari / tethered cord / post-traumatic etiology
  • Spinal dural AVF: progressive myelopathy from venous hypertension → conus medullaris T2 hyperintensity + serpiginous dorsal flow voids; surgical clipping or endovascular embolization
  • Spondylolisthesis: degenerative (older, L4–L5) vs isthmic (young, pars defect at L5–S1) → FUSION if neurologic deficit + significant slip / instability
🔍 Quick ReferenceClinical · Imaging / decision · Surgical approach
Clinical clues
  • Saddle anesthesia + urinary retention + bilateral LE weaknessCauda equina syndrome
  • Hand clumsiness + gait imbalance + Hoffmann/Babinski + LhermitteCervical myelopathy
  • Shopping-cart sign / better with flexion-sitting, worse with standing-walkingNeurogenic claudication from lumbar stenosis
  • Tussive (Valsalva-induced) occipital headache + neck pain ± ataxiaChiari malformation type I
  • Suspended bilateral UE dissociated sensory loss + LMN weakness ± Charcot jointsSyringomyelia
  • Paraplegia + bilateral pain/temp loss with preserved proprioception/vibration after aortic surgeryAnterior spinal cord infarction
  • Back pain + fever + neuro deficit in IVDU/diabeticSpinal epidural abscess
  • Progressive lower-extremity myelopathy in older man, often misdiagnosed as stenosisSpinal dural AVF
Imaging / decision
  • Cerebellar tonsils >5 mm below foramen magnum on sagittal MRIChiari I (consider suboccipital decompression)
  • T2 cord hyperintensity at compression levelCervical myelopathy — surgical indication
  • Serpiginous dorsal flow voids + conus T2 hyperintensitySpinal dural AVF
  • Central canal expansion with fluid-filled cavity / cyst within cordIntramedullary tumor (ependymoma, astrocytoma) vs syrinx
  • Eccentric dural-based extramedullary massMeningioma / schwannoma (intradural extramedullary)
  • Vertebral body destruction / pedicle erosion with epidural soft tissueExtradural metastasis — STAT dexamethasone + MRI whole spine
  • Pars interarticularis defect on oblique X-ray (“Scotty dog collar”)Isthmic spondylolisthesis
  • Rim-enhancing dorsal epidural collection on MRI with contrastSpinal epidural abscess
Surgical approach / pearls
  • ACDF (Smith-Robinson)1–2 level anterior cervical disc/myelopathy — workhorse cervical operation
  • Laminoplasty≥3 level cervical stenosis with PRESERVED lordosis (fails in kyphosis — cord can’t drift back)
  • Laminectomy + posterior fusionMultilevel cervical stenosis with kyphosis or instability
  • TLIF vs PLIFTLIF (unilateral, less neural retraction) is the most popular lumbar fusion; PLIF for central pathology
  • ALIFBest access to L5–S1 (LLIF/XLIF blocked by iliac crest); watch for vascular injury and retrograde ejaculation
  • Suboccipital decompression ± duraplastyChiari I with symptoms or syrinx
  • Surgical clipping or endovascular embolizationSpinal dural AVF
  • Pedicle screws + rods (instrumentation)Fusion construct — watch for pseudarthrosis, hardware failure, adjacent segment disease, infection
Anterior vs. Posterior Approach

Decision Framework

  • Key principle: approach from the direction of the compressive pathology
  • Anterior compression (disc herniation, osteophyte, vertebral body pathology) → anterior approach
  • Posterior compression (ligamentum flavum hypertrophy, facet overgrowth, multilevel stenosis) → posterior approach
  • Circumferential compression: may require combined or staged approach
  • Other factors: number of levels, sagittal alignment (lordosis vs. kyphosis), prior surgery, medical comorbidities

Cervical Spine Approaches

ApproachProcedureIndicationsKey Points
AnteriorACDF (Anterior Cervical Discectomy & Fusion)1–2 level disc herniation, cervical radiculopathy/myelopathy from anterior compressionMost commonly performed cervical spine surgery; removes disc + fuses adjacent vertebrae with graft/plate; Smith-Robinson approach
AnteriorCervical corpectomyVertebral body pathology, retrovertebral disc, OPLL spanning disc space, tumorRemoves entire vertebral body + adjacent discs; higher pseudarthrosis rate than ACDF
AnteriorCervical disc replacement (arthroplasty)Single/two-level cervical disease in appropriate candidatePreserves motion; may reduce adjacent segment disease; contraindicated if facet arthropathy, instability, or ossification
PosteriorLaminectomy + fusion≥3 level cervical stenosis; any alignmentWide decompression; requires fusion with lateral mass or pedicle screws to prevent post-laminectomy kyphosis
PosteriorLaminoplasty≥3 level cervical stenosis; preserved lordosis requiredExpands canal without removing lamina (open-door or French-door technique); preserves motion; NOT for kyphotic spines

Lumbar Spine Approaches

ApproachProcedureKey Features
PosteriorPLIF (Posterior Lumbar Interbody Fusion)Bilateral approach through the spinal canal; higher retraction of neural elements; good for central pathology
PosteriorTLIF (Transforaminal Lumbar Interbody Fusion)Unilateral approach through the foramen; less neural retraction than PLIF; most popular lumbar fusion technique
LateralLLIF/XLIF (Lateral/Extreme Lateral Interbody Fusion)Traverses psoas muscle; risk of lumbar plexus injury; cannot access L5–S1 (iliac crest blocks access); good for coronal deformity correction
AnteriorALIF (Anterior Lumbar Interbody Fusion)Retroperitoneal or transperitoneal approach; best access to L5–S1; risk of vascular injury (iliac vessels), retrograde ejaculation in males

ACDF Complications

  • Recurrent laryngeal nerve injury: hoarseness; historically taught to be more common with right-sided approach due to RLN course variability, but current evidence shows no significant difference between sides. Surgeon preference and prior neck surgery typically dictate side. Transient in most cases.
  • Dysphagia: most common complication — early postoperative dysphagia up to 50% (most resolves over weeks to months); persistent dysphagia at 1 year ~5–15%
  • Esophageal perforation: rare but serious
  • Vertebral artery injury: rare; risk with far-lateral dissection
  • Adjacent segment disease: long-term degeneration above/below the fusion
💎 Board Pearl
  • ACDF is the most commonly performed cervical spine surgery and the first-line surgical option for 1–2 level anterior cervical pathology
  • Laminoplasty requires preserved cervical lordosis — it will not work in kyphotic spines because the cord cannot drift posteriorly away from anterior compression
  • LLIF/XLIF cannot access L5–S1 due to the iliac crest; ALIF is preferred for this level
  • Recurrent laryngeal nerve palsy was historically taught to be more common with right-sided ACDF due to RLN course variability, but current evidence shows no significant difference between sides — side selection is now driven by surgeon preference and prior neck surgery
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